Acrivastine

Acrivastine is a medication used for the treatment of allergies and hay fever. It is a second-generation H1-receptor antagonistantihistamine (like its base molecule triprolidine) and works by blocking Histamine H1 receptors.

This non-sedating^{[verification needed]} antihistamine is sold under the brand name Benadryl Allergy Relief in the United Kingdom byMcNeil Laboratories, not to be confused with Benadryl Once a Day, which is cetirizine and is also sold by McNeil in the UK. It is available as an over-the-counter medication in the UK, also offered with pseudoephedrine under the Benadryl brand

In the U.S., acrivastine is the active ingredient in the Semprex brand. Semprex-D is also acrivastine-based, but contains adecongestant, pseudoephedrine. Semprex-D is marketed in the U.S. by Actient Pharmaceuticals.^[1]

Comparisons with other popular antihistamines[edit]

Unlike cetirizine or loratadine, the standard dosage of which is one tablet every day, a single acrivastine tablet may be taken up to three times a day.^[2] Not to be taken by over 65's, pregnant women or people with compromised liver or kidney function.