Medroxyprogesterone (INN, BAN), also known as 17α-hydroxy-6α-methylprogesterone, and abbreviated as MP, is a steroidal progestin drug which was never marketed for use in humans.[1] An acylated derivative, medroxyprogesterone acetate (MPA), is clinically used as a pharmaceutical medicine.[2] Compared to MPA, MP is over two orders of magnitude less potent as a progestogen.[3] As such, MP itself is not used clinically, though it has seen limited use in veterinary medicine under the trade name Controlestril in France.[4] In addition, it is a metabolite of MPA.[5]
While medroxyprogesterone is sometimes used as a synonym for medroxyprogesterone acetate,[2] what is normally being administered is MPA and not MP.[6]
While medroxyprogesterone is sometimes used as a synonym for medroxyprogesterone acetate,[2] what is normally being administered is MPA and not MP.[6]
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